Researchers wanted to see if using a nozzle that sprayed a gentler mist for nasal sprays would improve the user experience and thus compliance. They found that a specific nozzle, the one used on Xlear Nasal Spray, provided an “unequivocally favorable experience.”
Basu, S., Khawaja, U., Rizvi, S., Sanchez-Gonzalez, M., & Ferrer, G. (2022). Evaluation of Patient Experience for a Computationally-Guided Intranasal Spray Protocol to Augment Therapeutic Penetration: Implications for Effective Treatments for COVID-19, Rhinitis, and Sinusitis. Medical Research Archives, 10(4).